5 Best NAD + supplements on the market

Why NAD+ Matters

NAD+ is a vital coenzyme found in all living cells, essential for converting nutrients into energy, regulating cellular processes, and protecting DNA. As we age, our natural NAD+ levels decline — which is why supplementing with NAD+ precursors like Nicotinamide Riboside (NR) and Nicotinamide Mononucleotide (NMN) can be a game-changer for energy, metabolism, and healthy aging.

Feel Energized from Within

NAD+ is essential for converting the food you eat into the energy your cells need to function. As we age, our NAD+ levels drop — leading to fatigue, slower metabolism, and poor cellular repair. Supplementing with a high-quality NAD+ formula helps restore vitality, boost daily energy, and keep you feeling sharp.

Sharpen Focus & Support Brain Health

NAD+ plays a crucial role in protecting brain cells, improving mental clarity, and supporting memory. Ingredients like Nicotinamide Riboside, Resveratrol, and PQQ have been shown to promote cognitive performance and protect against age-related decline.

Support Healthy Aging at the Cellular Level

NAD+ is vital for DNA repair, mitochondrial function, and overall cellular health — all key factors in slowing the aging process. By replenishing NAD+ levels, you help your body fight oxidative stress, improve resilience, and maintain peak performance as you age.

To help you choose the most effective NAD+ supplement, our expert review team has analyzed over 27 popular brands on the market today. After careful evaluation based on quality, potency, ingredient integrity, transparency, and user feedback, we’ve narrowed it down to the top 5 best NAD+ supplements of 2025.

  • Price: $ 39
  • Official Site: Buy Now
  • Guarantee: 100% Money Back
Overall Rating 99%
Effectiveness 98%
Speed of Results 97%
Ingredient Quality 98%
Long-Term Results 99%

Pros

    • Clinically dosed 300mg Nicotinamide Riboside Chloride (NRC) for powerful NAD+ support
    • Includes Resveratrol, PQQ, Pterostilbene, and Grape Seed Extract for antioxidant and mitochondrial support
    • Enhanced with Black Pepper Extract to maximize nutrient absorption and effectiveness
    • Promotes cellular energy, metabolic function, brain clarity, and healthy aging
    • Features key nutrients including Vitamin B6, B12, Magnesium, and Betaine Anhydrous
    • Gluten-free, cruelty-free, vegan, and made with no synthetic additives or fillers
    • Produced in a GMP-certified facility in the USA for premium quality and safety
    • No proprietary blends — full ingredient transparency
    • Backed by a 30-day money-back guarantee and 24/7 customer support

Cons

  • Only available online

Product Description:

ETA NATURE NAD+ is a next-generation supplement designed to revitalize your cells, recharge your energy, and help you age with strength and clarity. Powered by a high-potency dose of 300mg Nicotinamide Riboside Chloride (NRC), a clinically studied NAD+ precursor, this formula helps restore your body’s natural coenzyme levels that decline with age—impacting energy, brain function, and cellular repair.

What makes ETA NATURE different is its science-driven synergy of ingredients. Each serving includes Resveratrol and PQQ to enhance mitochondrial performance and antioxidant activity, while Pine Bark Extract and Grape Seed Extract provide cellular protection and circulation support. Black Pepper Extract ensures maximum absorption, and essential nutrients like Vitamin B6, B12, Magnesium, Pterostilbene, and Betaine Anhydrous support energy metabolism, detoxification, and cognitive clarity at every level.

Customers love the difference they feel—more daily energy, sharper focus, improved recovery, and long-term vitality. Unlike many competitors, our formula contains no proprietary blends or hidden fillers, and is proudly gluten-free, cruelty-free, vegan-friendly, and free from synthetic additives. Every bottle is made in the USA in GMP-certified facilities to ensure unmatched quality, purity, and transparency.

With a 30-day money-back guarantee and 24/7 customer service, your satisfaction is fully protected. If you’re serious about wellness, longevity, and real cellular performance, ETA NATURE NAD+ delivers on every front—experience the difference your body deserves.

Key Ingredients:

  • Nicotinamide Riboside Chloride (300mg)
  • Resveratrol (250mg)
  • PQQ (10mg)
  • Grape Seed Extract (100mg)
  • Pine Bark Extract (100mg)
  • Black Pepper Extract (5mg)
  • Vitamin B6 & B12
  • Magnesium
  • Pterostilbene
  • Betaine Anhydrous
  • Price: $ 39
  • Official Site: Buy Now
  • Guarantee: 100% Money Back
Overall Rating 95%
Effectiveness 97%
Speed of Results 96%
Ingredient Quality 97%
Long-Term Results 98%

Pros

  • Backed by clinical studies and scientific institutions
  • Clean, single-ingredient formula
  • Available in multiple dosage options

Cons

  • Lacks supporting co-factors like Resveratrol or PQQ

Product Description:

Tru Niagen is a well-known brand with significant scientific backing. It contains Nicotinamide Riboside (NR) as its sole active ingredient, making it ideal for purists who want a targeted NAD+ boost without extras. It’s been featured in over a dozen published clinical trials and is trusted by longevity researchers.

Key Ingredients:

  • Nicotinamide Riboside (NR)
  • Price: $ 60
  • Official Site: Buy Now
  • Guarantee: 100% Money Back
Overall Rating 90%
Effectiveness 92%
Speed of Results 91%
Ingredient Quality 92%
Long-Term Results 93%

Pros

  • Clinically supported ingredients
  • Clean, athlete-approved formulation
  • Includes antioxidant and methylation support

Cons

  • Somewhat lower NR dosage compared to competitors

Product Description:

Thorne’s ResveraCel combines Nicotinamide Riboside with Resveratrol, Quercetin, and Betaine to support NAD+ production, cardiovascular health, and antioxidant protection. It’s NSF-certified for sport, making it a top choice for athletes or anyone seeking high standards in purity and performance.

Key Ingredients:

  • Nicotinamide Riboside
  • Resveratrol
  • Quercetin
  • Betaine Anhydrous
  • Price: $ 60
  • Official Site: Buy Now
  • Guarantee: 100% Money Back
Overall Rating 91%
Effectiveness 92%
Speed of Results 91%
Ingredient Quality 91%
Long-Term Results 90%

Pros

  • Co-developed by world-renowned researchers
  • Backed by internal scientific studies
  • Convenient subscription model

Cons

  • Proprietary blend doesn’t disclose exact ingredient amount

Product Description:

Elysium Basis is co-developed with MIT scientists and features a blend of Nicotinamide Riboside and Pterostilbene, a powerful antioxidant similar to resveratrol but with better bioavailability. The brand is well known in the longevity space and offers subscription-based convenience.

Key Ingredients:

  • Nicotinamide Riboside
  • Pterostilbene
  • Price: $ 18
  • Official Site: Buy Now
  • Guarantee: 100% Money Back
Overall Rating 89%
Effectiveness 90%
Speed of Results 88%
Ingredient Quality 89%
Long-Term Results 92%

Pros

  • Affordable and widely available
  • Third-party tested
  • Trusted supplement brand

Cons

  • Lower NR dosage than premium products
  • No synergistic ingredients included

Product Description:

Life Extension offers a simple and effective NR-based supplement at an affordable price. It provides 100mg of Nicotinamide Riboside per capsule, making it a great entry-level option for those curious about NAD+ without a high upfront investment.

Key Ingredients:

  • Nicotinamide Riboside (100mg)

Top NAD + supplements on the market

Overall Value: 97 /100 97%

If you're serious about aging better, thinking sharper, and performing at your peak, NAD+ supplementation is a smart step forward. And ETA NATURE NAD+ leads the way with the most complete, potent, and synergistic formula on the market.

If you're serious about aging better, thinking sharper, and performing at your peak, NAD+ supplementation is a smart step forward. And ETA NATURE NAD+ leads the way with the most complete, potent, and synergistic formula on the market.